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¿µ³²ÀÇ´ëÇмúÁö Vol.28 No.1 p1-12, June2011
Review

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Combined Hepatocellular-Cholangiocarcinoma: Recent Progress in Pathology and Classification
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Tel: (053) 620-3335, FAX: (053) 656- 1429
E-mail : joonhyukchoi@ynu.ac.kr

June 30, 2011

Abstract

Primary liver carcinomas have been classified into hepatocellular carcinoma, cholangiocarcinoma, and combined hepatocellular-cholangiocarcinoma (CHC). CHC is a tumor containing unequivocal, intimately mixed elements of both hepatocellular carcinoma and cholangiocarcinoma. It forms a small but significant proportion of primary liver carcinomas. The origin and pathogenesis of CHC have not been well established. According to the 2010 WHO classification, CHCs are categorized into 2 groups: the classical type and a subtype with stem cell features. This review describes recent progress in pathology and classification of CHC.

Key Words: Liver, Combined hepatocellular-cholangiocarcinoma, Immunohistochemistry, Stem cell, Classification

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